Polynucleotide

A revolutionary regenerative injectable designed to heal and revitalize skin at a cellular level

Polynucleotide treatments are  a revolutionary regenerative injectable designed to heal and revitalize skin at a cellular level. Derived from purified salmon or trout DNA, these biostimulators trigger the body’s natural repair mechanisms to stimulate collagen, boost hydration, and improve skin elasticity. 

Key Benefits

Instead of just filling or temporarily plumping the skin, polynucleotides work by prompting your cells to self-repair and regenerate:

  • Improved Texture & Firmness: Stimulates fibroblasts to produce new collagen and elastin, lifting and tightening loose or crepey skin.
  • Deep Hydration: The DNA chains attract and bind water molecules within the skin tissue, locking in long-lasting moisture.
  • Scar & Stretch Mark Reduction: Scientifically shown to improve the appearance of acne scarring and stubborn stretch marks.
  • Under-Eye Brightening: Highly effective at treating dark circles, hollows, and fine lines in the delicate eye area.

How It Compares to Other Treatments

Polynucleotide vs Dermal Fillers

While fillers add immediate volume to a specific area, polynucleotides rely on your body to rebuild its own foundational structure over time. 

Polynucleotide vs Botox

Botox temporarily freezes facial muscles to stop wrinkles, whereas polynucleotides improve the actual health, thickness, and elasticity of the skin itself.

Why Choose
Doctor SR?

Choosing a doctor-led clinic means choosing medical accountability. With over 20 years of clinical experience, Dr. Rahman combines an artist’s eye with a GP’s commitment to patient safety.

FAQs

Doctor‑led answers for patients exploring regenerative skin treatments in Cardiff.

Polynucleotides are one of the fastest‑growing regenerative treatments in aesthetics, known for improving skin quality, hydration, elasticity, and under‑eye texture. Below are the questions patients most often ask during consultations.

What are polynucleotides?

Polynucleotides are highly purified DNA fragments derived from natural sources. When injected into the skin, they stimulate cell repair, collagen production, hydration, and tissue regeneration, helping improve overall skin quality.

Polynucleotides are ideal for improving:

- Under‑eye hollowness or crepey texture
- Fine lines
- Skin laxity
- Dull or dehydrated skin
- Acne scarring
- Overall skin quality and elasticity
- Early signs of ageing

They are often chosen when patients want natural‑looking, subtle rejuvenation.

They act on the skin in several ways:

- Stimulating fibroblasts to produce collagen and elastin
- Improving hydration by increasing water‑binding capacity
- Reducing inflammation and supporting tissue repair
- Enhancing skin elasticity over time

The result is healthier, firmer, more radiant skin.

Common treatment areas include:

- Under‑eyes
- Full face
- Neck
- Décolletage
- Hands
- Acne‑scarred areas

The under‑eye region is one of the most popular due to its delicate nature and excellent response.

Most patients notice improvements gradually over 3–6 weeks, with continued enhancement over several months as collagen production increases.

A typical treatment plan involves 2–3 sessions, spaced 2–4 weeks apart.Maintenance sessions every 6–12 months help sustain results.

Yes. Polynucleotides have been used in medicine for decades and have a strong safety profile when administered by a trained medical professional.Your consultation includes a full assessment to ensure suitability.

Most patients experience only mild discomfort. Very fine needles are used, and numbing can be applied if needed.

Results typically last 6–12 months, depending on your skin quality, lifestyle, and maintenance plan.

No - although they are often compared.

- Skin boosters mainly hydrate the skin using hyaluronic acid.
- Polynucleotides stimulate regeneration, collagen, and tissue repair.

They can be used together for enhanced results.

Yes. They pair well with:

- Skin boosters
- Chemical peels
- Microneedling
- Anti‑wrinkle treatments
- Light‑based therapies

Your treatment plan is tailored to your goals and skin needs.

Yes — they are suitable for all skin tones and most skin types.Your consultation ensures the treatment is appropriate for your medical history and concerns.

No. Polynucleotides are not recommended during pregnancy or breastfeeding.

Polynucleotides create subtle, natural improvements. Most patients simply look fresher and more rested over time.